1-piperidinecarboxylic acid, 4-(2-ethoxy-2-oxoethylidene)-
tert-Butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate
CAS: 135716-08-4
Molecular Formula: C14H23NO4
1-piperidinecarboxylic acid, 4-(2-ethoxy-2-oxoethylidene)- - Names and Identifiers
1-piperidinecarboxylic acid, 4-(2-ethoxy-2-oxoethylidene)- - Physico-chemical Properties
| Molecular Formula | C14H23NO4 |
| Molar Mass | 269.34 |
| Density | 1.129 |
| Melting Point | 85 °C |
| Boling Point | 354℃ |
| Flash Point | 168℃ |
| pKa | -1.46±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD12912655 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
1-piperidinecarboxylic acid, 4-(2-ethoxy-2-oxoethylidene)- - Risk and Safety
| Hazard Class | IRRITANT |
1-piperidinecarboxylic acid, 4-(2-ethoxy-2-oxoethylidene)- - Introduction
tert-Butyl 4-(2-ethoxy-2-oxoethylidene) piperidine-l-carboxylate tert-butyl ester, chemical formula C15H27NO4, is also known as piperidine ester tert-butyrate. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless or light yellow liquid.
-Density: about 0.97g/cm³.
-Boiling point: about 290 ℃.
-Melting point: about -68 ℃.
-Solubility: Soluble in organic solvents, such as ethanol, ether, etc.
Use:
-tert-Butyl 4-(2-ethoxy-2-oxoethylidene) piperidine-1-carboxylic acid tert-butyl ester is mainly used as a pharmaceutical intermediate and can be used in the synthesis of certain drugs.
Preparation Method:
The synthesis of tert-butyl 4-(2-ethoxy-2-oxoethylidene) piperidine -1-carboxylic acid tert-butyl ester can be completed by the following steps: first, tert-butyl aerobic piperidine formate The salt reacts with ethyl fluoroalcohol to generate the corresponding ethyl fluoroether compound; then, the obtained ethyl fluoroether is transesterified with tert-butyl formate; finally, the obtained product is subjected to esterification reaction by acid catalysis to obtain the target product.
Safety Information:
-The compound may cause irritation and corrosion to the human body, so appropriate personal protective measures should be taken, such as wearing gloves and protective clothing.
-Avoid contact with skin and eyes, use safety glasses and protective mask if necessary.
-Avoid contact with oxidants, acids and alkalis during use and storage.
-If the substance is inhaled or ingested, seek medical attention immediately and show your safety data sheet to your doctor.
Nature:
-Appearance: Colorless or light yellow liquid.
-Density: about 0.97g/cm³.
-Boiling point: about 290 ℃.
-Melting point: about -68 ℃.
-Solubility: Soluble in organic solvents, such as ethanol, ether, etc.
Use:
-tert-Butyl 4-(2-ethoxy-2-oxoethylidene) piperidine-1-carboxylic acid tert-butyl ester is mainly used as a pharmaceutical intermediate and can be used in the synthesis of certain drugs.
Preparation Method:
The synthesis of tert-butyl 4-(2-ethoxy-2-oxoethylidene) piperidine -1-carboxylic acid tert-butyl ester can be completed by the following steps: first, tert-butyl aerobic piperidine formate The salt reacts with ethyl fluoroalcohol to generate the corresponding ethyl fluoroether compound; then, the obtained ethyl fluoroether is transesterified with tert-butyl formate; finally, the obtained product is subjected to esterification reaction by acid catalysis to obtain the target product.
Safety Information:
-The compound may cause irritation and corrosion to the human body, so appropriate personal protective measures should be taken, such as wearing gloves and protective clothing.
-Avoid contact with skin and eyes, use safety glasses and protective mask if necessary.
-Avoid contact with oxidants, acids and alkalis during use and storage.
-If the substance is inhaled or ingested, seek medical attention immediately and show your safety data sheet to your doctor.
Last Update：2024-04-09 21:01:54
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Product Name: tert-butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate Visit Supplier Webpage Request for quotation
CAS: 135716-08-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 135716-08-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
1-piperidinecarboxylic acid, 4-(2-ethoxy-2-oxoethylidene)-
p-METHOXYAZOBENZENE extrapure AR
Solvent Blue 63
p-METHOXYAZOBENZENE extrapure AR
Solvent Blue 63